DailyMed - ELIQUIS- apixaban tablet, film coated ELIQUIS ...
Apixaban is metabolized mainly via CYP3A4 with minor contributions from CYP1A2, 2C8, 2C9, 2C19, and 2J2. O-demethylation and hydroxylation at the 3-oxopiperidinyl moiety are the major sites of biotransformation. Unchanged apixaban is the major drug-related component in human plasma; there are no active circulating metabolites.
DA: 39 PA: 55 MOZ Rank: 89 Up or Down: Up