ewsr1 | EWSR1 Gene - GeneCards | EWS Protein

Keyword	CPC	PCC	Volume	Score	Length of keyword
ewsr1	0.59	0.2	2985	19	5

Keyword	CPC	PCC	Volume	Score
ewsr1	1.92	0.9	8230	60
ewsr1-fli1	0.8	0.9	8663	30
ewsr1 gene	0.25	0.9	4968	52
ewsr1-atf1	1.38	0.6	1066	39
ewsr1 fusion	1.72	0.6	9432	65
ewsr1-wt1	1.25	1	1155	20
ewsr1 fish	1.43	0.7	3076	85
ewsr1-smad3	1.55	0.8	3643	4
ewsr1-erg	1.52	1	7085	45
ewsr1-creb1	1.95	0.6	8021	51
ewsr1 gene rearrangement	1.01	0.2	4892	84
ewsr1-fli1 fusion	1.02	0.3	9083	83

Search Results related to ewsr1 on Search Engine

EWSR1 Gene - GeneCards | EWS Protein | EWS Antibody
genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=EWSR1

WEBApr 3, 2024 · EWSR1 (EWS RNA Binding Protein 1) is a Protein Coding gene. Diseases associated with EWSR1 include Ewing Sarcoma and Desmoplastic Small Round Cell Tumor . Among its related pathways are Translational Control and BARD1 signaling events .

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EWSR1 gene: MedlinePlus Genetics
medlineplus.gov

https://medlineplus.gov/genetics/gene/ewsr1/

WEBThe EWSR1 gene provides instructions for making the EWS protein, whose function is not completely understood. Learn about this gene and related health conditions.

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EWSR1, a multifunctional protein, regulates cellular function and …
nih.gov

https://pubmed.ncbi.nlm.nih.gov/30481590/

WEBJul 1, 2019 · Abstract. Ewing's sarcoma (EWS) is a bone cancer arising predominantly in young children. EWSR1 (Ewing Sarcoma breakpoint region 1/EWS RNA binding protein 1) gene is ubiquitously expressed in most cell types, indicating it has diverse roles in various cellular processes and organ development.

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EWSR1—The Most Common Rearranged Gene in Soft Tissue …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232650/

WEBJun 15, 2021 · EWSR1 is a multifunctional protein ubiquitously expressed in most cell types, indicating diverse roles in physiological cellular processes, including organ development and aging. Genetic and epigenetic pathways are modulated by EWSR1 but the exact mechanisms are still poorly understood [ 2 ].

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EWSR1, a multifunctional protein, regulates cellular function and …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527469/

WEBJul 1, 2019 · Highlights. EWSR1 (Ewing Sarcoma breakpoint region 1/EWS RNA binding protein 1) has diverse roles in various cellular processes such as gene expression and RNA processing, and organ development. Missense mutations of EWSR1 genes are associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

DA: 82 PA: 85 MOZ Rank: 72 Up or Down: Up

EWSR1 fusions: Ewing sarcoma and beyond - Jo - 2020 - Cancer
wiley.com

https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncy.22239

WEBJan 29, 2020 · EWSR1 forms fusion genes with a wide spectrum of partner genes among clinicopathologically diverse soft-tissue tumors, as well as specific carcinomas and a subset of mesothelioma (Fig 1 ), and the list of tumor types with EWSR1 rearrangements and fusion partners continues to grow.

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EWSR1 EWS RNA binding protein 1 [ (human)] - National Center …
nih.gov

https://www.ncbi.nlm.nih.gov/gene/2130

WEBSummary. This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain.

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EWSR1, a multifunctional protein, regulates cellular function and …
sciencedirect.com

https://www.sciencedirect.com/science/article/pii/S0925443918304794

WEBJul 1, 2019 · EWSR1 (Ewing Sarcoma breakpoint region 1/EWS RNA binding protein 1) has diverse roles in various cellular processes. •. Missense mutations of EWSR1 are associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). •. EWSR1 deficiency also contributes to hematopoietic stem cell senescence. •.

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A Rare Case of a Malignant Epithelioid Neoplasm With an …
sagepub.com

https://journals.sagepub.com/doi/full/10.1177/10668969241246462

WEB1 day ago · Le Loarer F, Szuhai K, Tirode F. Round cell sarcomas with EWSR1-non ETS fusions. Undifferentiated small round cell sarcomas of bone and soft tissue. In: World Health Organization classification of tumors (WHO) editorial board (eds) WHO Classification of tumors . 5th ed. IARC Press; 2020:326-329.

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Therapeutic targeting the oncogenic driver EWSR1::FLI1 in
nature.com

https://www.nature.com/articles/s41388-022-02533-1

WEBNov 10, 2022 · The FACT inhibitor drug CBL0137 effectively targets the EWSR1::FLI1-FACT circuit, resulting in transcriptional disruption of EWSR1::FLI1, SSRP1 and their downstream effector oncogenic...

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