cefiderocol generation | Cefiderocol, a new antibiotic against multidr

Keyword	CPC	PCC	Volume	Score	Length of keyword
cefiderocol generation	0.41	0.8	1126	89	22
cefiderocol	1.06	0.5	2123	73	11
generation	0.59	0.5	6703	11	10

Keyword	CPC	PCC	Volume	Score
cefiderocol generation	0.42	1	1834	62
cefiderocol generation cephalosporin	0.41	1	1799	53
what generation is cefiderocol	0.48	0.1	404	54
what generation cephalosporin is cefiderocol	1.19	0.4	3148	42
cefiderocol 5th generation	1.93	0.5	2628	83
cefiderocol fifth generation	1.23	0.9	4284	15
cefiderocol 5th generation cephalosporin	1.37	0.5	3494	36

Search Results related to cefiderocol generation on Search Engine

Cefiderocol, a new antibiotic against multidrug-resistant Gram …
nih.gov:443

https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC8683016/

WEBJan 12, 2021 · Cefiderocol is a novel cephalosporin with a promising activity against MDR GNB, including carbapenem-resistant GNB. It would be especially useful for the treatment of GNB with limited therapeutic options as those producing metal-loβ-lactamases.

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Cefiderocol - Wikipedia
wikipedia.org:443

https://en.wikipedia.org:443/wiki/Cefiderocol

WEBCefiderocol, sold under the brand name Fetroja among others, is an antibiotic used to treat complicated urinary tract infections when no other options are available. It is indicated for the treatment of multi-drug-resistant Gram-negative bacteria including Pseudomonas aeruginosa .

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Cefiderocol: A Novel Agent for the Management of Multidrug …
nih.gov:443

https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC7054475/

WEBFeb 18, 2020 · Cefiderocol is a newly US FDA-approved, first in its class, siderophore cephalosporin with potent in vitro activity against CRE and drug-resistant non-fermenting Gram-negative bacilli.

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Cefiderocol: A Siderophore Cephalosporin with Activity Against ... - PubMed
nih.gov:443

https://pubmed.ncbi.nlm.nih.gov:443/30712199/

WEBThe chemical structure of cefiderocol is similar to both ceftazidime and cefepime, which are third- and fourth-generation cephalosporins, respectively, but with high stability to a variety of β-lactamases, including AmpC and extended-spectrum β-lactamases (ESBLs).

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Cefiderocol: A Review in Serious Gram-Negative Bacterial Infections
nih.gov:443

https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC8383240/

WEBAug 24, 2021 · Cefiderocol (Fetroja ®; Fetcroja ®), an intravenously infused siderophore cephalosporin with a unique mechanism of bacterial cell entry, is approved in the EU and the USA for the treatment of adults with Gram-negative bacterial infections (Sect. 6). This article reviews the efficacy and tolerability of cefiderocol in the approved indications ...

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Cefiderocol: Discovery, Chemistry, and In Vivo Profiles of a Novel
oup.com:443

https://academic.oup.com:443/cid/article/69/Supplement_7/S538/5624004

WEBNov 13, 2019 · Cefiderocol is a novel siderophore cephalosporin targeting gram-negative bacteria, including strains with carbapenem resistance. The structural characteristics of cefiderocol show similarity to both ceftazidime and cefepime, which enable cefiderocol to withstand hydrolysis by β-lactamases.

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New Cephalosporins: Fifth and Sixth Generations | SpringerLink
springer.com:443

https://link.springer.com:443/chapter/10.1007/978-3-031-26078-0_2

WEBMay 26, 2023 · Cefiderocol is the latest novel 5th–6th generation cephalosporin to be approved by the FDA in November 2019 for the treatment of complicated urinary tract infections (UTIs) and pyelonephritis, and in September 2020 it was approved for hospital-acquired and ventilator-associated bacterial pneumonia (HAP/VAP).

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Cefiderocol: a novel siderophore cephalosporin for multidrug
nih.gov:443

https://pubmed.ncbi.nlm.nih.gov:443/33532823/

WEBMay 12, 2021 · PMID: 33532823. DOI: 10.1093/jac/dkab015. Abstract. Cefiderocol is a novel siderophore cephalosporin that forms a complex with extracellular free ferric iron, which leads to transportation across the outer cell membrane to exert its bactericidal activity through cell wall synthesis inhibition.

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Cefiderocol: a novel siderophore cephalosporin - PubMed
nih.gov:443

https://pubmed.ncbi.nlm.nih.gov:443/29318906/

WEBOur understanding of multidrug-resistance and bacterial biochemical pathways continues to expand, and the development of cefiderocol specifically targeting siderophore-mediated iron transport shows potential in escaping mechanisms of drug resistance.

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Cefiderocol in context - The Lancet Infectious Diseases
thelancet.com:443

https://www.thelancet.com:443/journals/laninf/article/PIIS1473-3099(18)30615-7/fulltext

WEBOct 25, 2018 · Angela Huttner. Published: October 25, 2018 DOI: https://doi.org/10.1016/S1473-3099 (18)30615-7. Cefiderocol in context. New antibiotics reaching clinical development are scarce, although bacterial plasmids encoding antibiotic resistance genes seem to be everywhere.

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